Ricin
The seeds from the castor bean plant, Ricinus communis, are poisonous to
people, animals and insects. One of the main toxic proteins is "ricin",
named by Stillmark in 1888 when he tested the beans' extract on red blood cells and saw
them agglutinate. Now we know that the agglutination was due to another toxin that was
also present, called RCA (Ricinus communis agglutinin). Ricin is a potent cytotoxin but
a weak hemagglutinin, whereas RCA is a weak cytotoxin and a powerful hemagglutinin.
Poisoning by ingestion of the castor bean is due to ricin, not
RCA, because RCA does not penetrate the intestinal wall, and does not affect red blood
cells unless given intravenously. If RCA is injected into the blood, it will cause the red
blood cells to agglutinate and burst by hemolysis.
Just one milligram of ricin can kill an adult.
The symptoms of human poisoning begin within a few hours of ingestion.
The symptoms are:
- abdominal pain
- vomiting
- diarrhea, sometimes bloody.
Within several days there is:
- severe dehydration,
- a decrease in urine,
- and a decrease in blood pressure.
If death has not occurred in 3-5 days, the victim usually recovers. It is
advisable to keep children away from the castor bean plant or necklaces made with its
seeds. In fact donít even have them in or around a house with small children. If they
ingest the leaves or swallow the seeds, they may get poisoned. The highly toxic seeds
beaded into necklaces, cause skin irritation at the contact point.
If the seed is swallowed without chewing, and there is no damage to the seed
coat, it will most likely pass harmlessly through the digestive tract. However, if it is
chewed or broken and then swallowed, the ricin toxin will be absorbed by the intestines.
It is said that just one seed can kill a child. Children are more
sensitive than adults to fluid loss due to vomiting and diarrhea, and can quickly become
severely dehydrated and die.
Ricin is a deadly tasteless, odourless poison. It is easily extracted from
castor beans. The guide available at this site teaches how this deadly poison can be
extracted and refined.
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